mRNA vaccines linked to increased risk of carditis | mRNA 疫苗與心臟炎風險增加有關

Another report can be read here

A case control study published in March 2022 in Annals of Internal Medicine reveals that receiving the mRNA covid vaccine BNT162b2 made by Pfizer–BioNTech could significantly increase risk of carditis – nine times more cases of myocarditis than cases of pericarditis. Use of the word could is because the study could not establish a causal relation between vaccination and elevated risk of carditis, which is still possible.

In the study conducted by Dr. Francisco Lai and colleagues from University of Hong Kong, a statistical analysis of data from 160 patients with carditis and 2200 patients without also shows that patients aged 12 to 17 years who received BNT162b2 had 17 times higher risk of carditis than those who did not. In adults aged 18 or older, the risk doubled.

The vaccine BNT162b2 increased a greater risk of carditis in males than in females; in males, the risk was increased by 4.68 times while in female by 2.2 times. The increase in the risk of carditis is primarily associated with the administration of the second shot, but not the first one. (Did not count on the booster).

This is not the first to reveal the association between vaccination with BNT162b2 and risk of carditis. A similar study conducted by researchers in Israel and published earlier came to the same conclusion that risk of carditis in patients receiving BNT162b2 is more than triple risk of carditis in those who did not receive the vaccine.  And the risk is greater in adolescents than in adults.  Some case reports published previously also linked cases of carditis to the vaccination with BNT162b2. Another European study also linked mRNA vaccines to elevated risk of carditis.

According to the current study report, symptoms of carditis in the vaccinated patients often manifest within the first 14 days of vaccination. This does not mean that risk disappears after 14 days of vaccination. Researchers of the current study suggested that mRNA vaccine recipients need to watch symptoms of carditis including chest pain, palpitation, short breath and subsequent elevated risk for carditis.

They played down the risk by pointing out that the increase of absolute risk is small. They also cited a report to show that covid 19 infection may increase risk of carditis by 19 times.  They meant to say that while of some concern, the risk is no big deal.

(Note that not all studies are trustworthy including the current one because of potential conflicts of interest or potential influence by the industry.  This study could underestimate the risk increase by vaccination of BNT162b2.  A study from Thailand indicates that mRNA vaccines could cause carditis in 30% of children vaccinated.)

The researchers also said no death or ICU care was associated with vaccination of BNT162b2.  However, this claim is irrelevant because their study was not intended to prove or disprove the link.   In fact,  deaths in vaccinated otherwise healthy individuals have been observed. Another report can be viewed on this subject.

This study also tried to determine if there is any association between use of CoronaVac (Sinovac) made by a Chinese company, and risk of carditis. Some analyses did reveal some increase in risk in patients receiving this vaccine although the increase is not as great as that from BNT162b2 . The Chinese vaccine, unlike the active mRNA vaccine BNT162b2, is sterilized. But the report says that there is no link between the vaccine and the risk of carditis.

Note that the study was focused on patients with clinically significant symptoms of carditis.  It is unknown how many people may be impacted by mRNA vaccines to develop sub-clinical heart conditions.

What you can do if you have received covid 19 vaccine? These things may help including 1) do not receive more vaccines. 2) avoid violent physical activities and improve your health conditions if you are suffering autoimmune diseases like diabetes, cardiovascular disease like hypertension, coronary heart disease, stroke, heart failure, myositis, and encephalitis, 3) do not use any foods, medications, and lifestyle that can increase risk of carditis or worsen your condition, 4) use supplements such as vitamin C, D, B complex, acetyl cysteine, quercetin, glutathione etc. and healthy natural whole foods such as green leafy vegetables and berries to minimize your systemic inflammation to prevent your condition from getting worse.

Read this article to understand how to prevent the adverse effects of mRNA vaccines.

2022 年 3 月發表在 Annals of Internal Medicine 上的一項病例對照研究表明，接受輝瑞-BioNTech 生產的 mRNA covid 疫苗 BNT162b2 可能會顯著增加患心髒病的風險——心肌炎病例是心包炎病例的 9 倍。 使用可能這個詞是因為該研究無法確定疫苗接種與心臟炎風險升高之間的因果關係，雖然這仍然是可能的。

在香港大學 Francisco Lai 博士及其同事進行的研究中，對 160 名心臟炎患者和 2200 名非心臟炎患者的數據進行統計分析也表明，接受 BNT162b2 的 12 至 17 歲患者患心臟炎的風險高出 17 倍 比那些沒有接受 BNT162b2的人。 在 18 歲或以上的成年人中，心臟炎風險加倍。

與女性相比，BNT162b2 疫苗增加男性患心臟炎的風險更大； 在男性中，心臟炎風險增加了 4.68 倍，而在女性中增加了 2.2 倍。 心臟炎風險的增加主要與第二次注射後，但與第一次接種疫苗不相關。

這並不是第一次揭示 BNT162b2 疫苗接種與心臟炎風險之間的關聯。 一項由以色列研究人員進行並較早發表的類似研究得出了相同的結論，即接受 BNT162b2 的患者患心臟炎的風險是未接種疫苗的患者患心臟炎的風險的三倍以上。 青少年的風險高於成人。 之前發表的一些病例報告也將心臟炎病例與 BNT162b2 疫苗接種聯繫起來。 另一項歐洲研究也將 mRNA 疫苗與心臟炎風險升高聯繫起來。

根據目前的研究報告，接種疫苗的患者心臟炎症狀往往在接種疫苗後的前14天內出現。 這並不意味著風險在接種疫苗 14 天后消失。 當前研究的研究人員建議，mRNA 疫苗接種者需要了解心臟炎的任何症狀，包括胸痛、心悸、呼吸急促和隨後心臟炎風險升高。

研究人員顯然不希望他們的研究得罪疫苗製造商。 他們通過指出絕對風險的增加很小來淡化風險。 他們還引用一份報告顯示，感染 covid 19 可能會使心臟炎的風險增加 19 倍。 他們的意思是說雖然有些擔憂，但mRNA 疫苗的風險沒什麼大不了的。

（請注意，由於潛在的利益衝突或行業的潛在影響，並非所有研究都值得信賴，包括當前的研究。這項研究可能低估了 BNT162b2 疫苗接種帶來的風險增加，但不太可能高估。來自泰國的一項研究表明，mRNA 疫苗可能導致 30% 的接種兒童發生心臟炎。）

研究人員還表示，沒有死亡或 ICU 護理與接種 BNT162b2 相關。 然而，這種說法是無關緊要的，因為他們的研究並不是為了證明或反駁這種聯繫。 事實上，已經觀察到在其他方面健康的人接種疫苗後死亡。 可以查看有關此主題的另一份報告。

該研究還試圖確定使用中國公司生產的 CoronaVac（Sinovac）與心臟炎風險之間是否存在任何關聯。 一些分析確實顯示接受這種疫苗的患者的風險有所增加。 儘管增幅沒有 BNT162b2 的增幅大。與活性mRNA疫苗BNT162b2不同，中國疫苗是滅菌的。 但報告稱疫苗與心臟炎風險之間沒有聯繫。

請注意，該研究的重點是具有臨床顯著心臟炎症狀的患者。 目前尚不清楚有多少人可能會受到 mRNA 疫苗的影響而發展為亞臨床心髒病。

如果您接種了 covid 19 疫苗，您可以做什麼？ 這些事情可能會有所幫助，包括 1) 不要接種更多疫苗。 2) 如果您患有糖尿病等自身免疫性疾病、高血壓等心血管疾病、冠心病、中風、心力衰竭、肌炎和腦炎，請避免劇烈運動並改善您的健康狀況， 3) 不要使用任何食物、藥物和 可能增加心臟炎風險或使您的病情惡化的生活方式，4) 使用維生素 C、D、B 複合物、乙酰半胱氨酸、槲皮素、穀胱甘肽等補充劑和綠葉蔬菜和漿果等健康天然天然食物，以盡量減少您的全身性 發炎，以防止您的病情惡化。

閱讀本文以了解如何預防 mRNA 疫苗的不良反應。