防火材料可导致早死 – Polychlorinated biphenyls linked to premature death risk

JAMA网络公开杂志上的一项研究表明,摄入大量多氯联苯(PCBs)的人可能有过早死亡的风险。

乌普萨拉大学的Lars Lind和Monica Lind教授以及厄勒布鲁大学的环境化学家对乌普萨拉1000名随机选择的70岁老人进行了一项调查,发现多氯联苯的高血液水平与过早死亡的风险之间存在相关性。

多氯联苯在过去被用作阻燃剂。其毒性促使许多国家多年前禁止使用这些化学品。但这些有毒化学物质具有持久性,至今仍可在污染环境中找到。

在这项研究中,研究人员对受试者进行了超过10年的研究,发现那些血液中多氯联苯的人死亡的可能性比血液中多氯联苯含量低的人高50%。

早期研究已将高PCB水平与人类和实验动物的动脉粥样硬化联系起来。

由于多氯联苯的毒性,另一组与多氯联苯相似的化学品多溴联苯用作阻燃剂。批评者指出,这些替代品可能与多氯联苯一样有毒,因为它们在化学上相似。

多氯联苯是脂溶性的。它们可以在高脂肪食物中发现,例如鱼类(污染区域的鲱鱼和鲑鱼),肉类和乳制品。植物来源的食物中含有较少的这些有毒化学物质。(陆博士)

A study in the JAMA Network Open journal suggests that people who have ingested high amounts of polychlorinated biphenyls (PCBs) may be at risk of premature death.

Professors Lars Lind and Monica Lind at Uppsala University and environmental chemists at Örebro University conducted a survey of 1000 randomly selected 70 year olds in Uppsala and found the link between high blood level of PCBs and risk of premature death.

PCBs had been used as a flame-retardant. Its toxicity has prompted many countries to ban these chemicals many years ago. But these toxic chemicals are persistent and can still be found in the polluted environment today.

For the study, the researchers followed the subjects for more than 10 years and found that those with high blood PCBs were 50% more likely to die than those with lower PCBs in their blood.

Early studies have linked high PCB levels to atherosclerosis in humans and experiment animals.

Because of the toxicity of PCBs, another group of chemicals polybrominated biphenyls which are similar to PCBs are used as flame-retardants. Critics point out that these replacements can be as toxic as PCBs because they are chemically similar.

PCBs are fat soluble. They can be found at high levels in fatty foods such as fish (herring and salmon in polluted areas), meat and dairy products. Plant-derived foods have much lower of these toxic chemicals. (Dr. Lu)

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