石榴汁抑制卵巢癌细胞的生长

2017年发表在癌症生物学和治疗学 (Cancer Biology and Therapy) 的一份研究报告表明,石榴汁 (pomegranate fruit juice),和它的两个主要活性成分:鞣花酸 (ellagic acid) 和木犀草素 (luteolin) 都能在体外抑制卵巢癌细胞的生长。

卵巢癌是女性生殖器官中第三大常见癌症,上皮性卵巢癌对所有妇科癌症的致死率最高。对此癌症, 西医没有什么好的疗法.

早期的研究已经表明,石榴果汁抑制卵巢癌以外的几种癌症的生长。对于目前的研究,研究人员将卵巢癌细胞系A2780暴露于石榴汁及其两种成分即鞣花酸和木犀草素。

该研究发现,所有三种治疗都抑制了卵巢癌细胞的增殖和迁移。裸鼠的初步研究表明,所有三种治疗都抑制肿瘤生长而没有副作用。

鞣花酸在抑制肿瘤生长方面比其他两种治疗更有效。

除卵巢癌外,鞣花酸还可用于对抗肺癌乳腺癌以及胶质瘤.

 

A research report published in 2017 in Cancer Biology and Therapy indicates that pomegranate juice and its two major anticancer ingredients namely ellagic acid and luteolin all inhibit the growth of ovarian cancer cells in vitro.

Ovarian cancer is common in the female reproductive organs and epithelial ovarian cancer is the most deadly malignancy among all gynecological cancers.

Early studies have already shown that pomegranate fruit juice inhibits the growth of several other cancer in addition to ovarian cancer.

For the current study, researchers exposed the ovarian cancer cell line A2780 to pomegranate fruit juice and ellagic acid and luteolin.

The study finds all three treatments effective at inhibiting the proliferation and migration of the ovarian cancer cells. Additional preliminary studies in nude mice show that all three treatments inhibit tumor growth without side effects.

Ellagic acid is particularly effective than other two agents at inhibiting the growth of the tumor.

In addition to ovarian cancer, ellagic acid may also be used to fight lung cancer, breast cancer and gliobastoma, according to previous studies.

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