维生素B2,B6和B12补充剂可降低2型糖尿病风险 Vitamins B2, B6 and B12 supplements may lower type 2 diabetes risk

维生素B2,B6和B12补充剂可降低2型糖尿病风险

来自哈佛大学的金。布劳恩博士与他的同事进行的一项研究表明维生素B2,B6,B12的补充剂可能可以减低2型糖尿病的风险。

该研究在2019年6月9日发布营养2019年会。它表明,与在最低的五分之一摄入量的男性和女性相比,维生素B2和B6摄入量最高的五分之一男性和女性被诊断为2型糖尿病的可能性分别降低了10%和11%。

该研究还表明,大量摄入维生素B12食物与2型糖尿病风险升高有关,而补充维生素B12则与降低该疾病的风险有关。

研究人员解释说,摄入大量维生素B12食物可能会增加2型糖尿病的风险,因为这些食物主要是动物性肉类食物。

研究作者提出,DNA甲基化与2型糖尿病的发展有关。 DNA甲基化可受甲基供体营养素如维生素B2,B6,B12,叶酸和蛋氨酸的影响。

但该研究未发现叶酸和蛋氨酸的摄入与2型糖尿病风险之间存在任何相关性。

该研究基于美国三项主要研究的数据,包括护士健康研究,护士健康研究II和卫生专业人员随访研究。

 

Vitamins B2, B6 and B12 supplements may lower type 2 diabetes risk

A study conducted by Kim V.E. Braun, Ph.D. and colleagues from Harvard University suggests vitamins B2 and B6 deficiency and supplementation of vitamin B12 may raise risk for type 2 diabetes.

Presented June 9, 2019 at Nutrition 2019, the study shows that men and women in the highest quintile of intakes of vitamin B2 and B6 were 10% and 11% less likely to be diagnosed with type 2 diabetes, respectively, compared to men and women in the lowest quintile of intake.

The study also reveals that high intake of vitamin B12 foods was associated with elevated risk for type 2 diabetes mellitus while vitamin B12 supplementation was linked to reduced risk for the health condition.

Study researchers explain that high intake of vitamin B12 foods may contribute to the increase in the risk of type 2 diabetes maybe because these foods are mostly animal meat-based foods.

Study authors suggest that DNA methylation has something to do with the development of type 2 diabetes. DNA methylation can be affected by methyl donor nutrients like vitamins B2, B6, B12, folate, and methionine.

But the study does not find any correlation between consumption of folate and methionine and the risk of type 2 diabetes mellitus.

The study was based on data from three major U.S. studies including the Nurses’ Health Study, the Nurses’ Health Study II and the Health Professionals Follow-up Study. (陆博士)

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