2型糖尿病可能影响亚洲种族心力衰竭患者的心脏结构,增加并发症和死亡 Type 2 diabetes may affect heart structure and increase complications and death among heart failure patients of Asian ethnicity

新闻稿201-AUG-2019
2型糖尿病可能影响亚洲种族心力衰竭患者的心脏结构,增加并发症和死亡
美国心脏协会

达拉斯 – 2019年8月21日 – 根据发表在美国心脏协会杂志上的一项新研究,2型糖尿病会影响心力衰竭患者的心脏结构并增加他们重复住院和/或死亡的风险.

2型糖尿病经常与心力衰竭共存,并且糖尿病的患病率在世界范围内增加。虽然糖尿病和心力衰竭在西方人群中得到了广泛的研究,但人们对亚洲人群的集体影响知之甚少。一个国际研究团队分析了参与ASIAN-HF研究的近6,200名心力衰竭患者的数据。

该研究发现患有2型糖尿病和心力衰竭与以下因素有关:

心脏结构异常;生活质量较差;并且在一年内增加了与心力衰竭相关的再次住院和/或死亡的风险。

研究人员还指出,这些心力衰竭患者中2型糖尿病的总患病率很高,超过40%患有糖尿病。新加坡和香港的患病率最高。

研究报告的共同作者Jonathan Yap,M.B.B.S.,M.P.H。,新加坡国家心脏中心心脏病科顾问说:“需要采取一级预防策略和量身定制的治疗方案来解决这一疾病的双重祸害。” “我们的研究结果强调了在社区和初级保健层面采取预防性公共卫生措施的必要性。对于患有糖尿病的心力衰竭患者,医生应密切监测和优化他们的管理。”

NEWS RELEASE 

Type 2 diabetes may affect heart structure and increase complications and death among heart failure patients of Asian ethnicity

AMERICAN HEART ASSOCIATION

DALLAS, August 21, 2019 — Type 2 diabetes affects the structure of the heart in heart failure patients and increases their risk for repeat hospitalizations and/or death, according to new research published in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Type 2 diabetes frequently coexists with heart failure, and the prevalence of diabetes has increased worldwide. While diabetes and heart failure together have been extensively studied among Western populations, there is less known about their collective impact among Asian populations. An international team of researchers analyzed data from more than nearly 6,200 heart failure patients participating in the ASIAN-HF Study.

The study found that having Type 2 diabetes and heart failure was associated with:

  • structural abnormalities in the heart;
  • poorer quality of life; and
  • increased risk of heart failure-related re-hospitalizations and/or death within one year.

Researchers also noted that the overall prevalence of Type 2 diabetes was high among these heart failure patients, with more than 40% having diabetes. The prevalence was highest in Singapore and Hong Kong.

“Primary prevention strategies and tailored treatment options are needed to tackle this twin scourge of diseases,” said study co-author Jonathan Yap, M.B.B.S., M.P.H., consultant from the department of cardiology of the National Heart Centre Singapore. “Our findings emphasize the need for preventative public health measures at the community and primary care level. For heart failure patients who have diabetes, physicians should closely monitor and optimize their management.”

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Co-authors are Wan Ting Tay, M.App.Stat.; Tiew-Hwa Katherine Teng, M.P.H., Ph.D.; Inder Anand, M.D., Ph.D.; A. Mark Richards, M.D., Ph.D.; Lieng Hsi Ling, M.B.B.S., M.D.; Michael R. MacDonald, M.B.Ch.B.; Chanchal Chandramouli, Ph.D.; Jasper Tromp, M.D., Ph.D.; Bambang B. Siswanto, M.D., Ph.D.; Michael Zile, M.D., Ph.D.; John McMurray, M.B.Ch.B. (Hons) M.D.; and Carolyn S.P. Lam, M.B.B.S., Ph.D.

Author disclosures are on the manuscript. The ASIAN-HF study is supported by grants from National Medical Research Council (NMRC) Singapore, Agency for Science, Technology and Research (A*STAR) Biomedical Research Council’s Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT) program, Boston Scientific Investigator Sponsored Research Program and Bayer.

Additional Resources:

Available multimedia is on right column of release link – https://newsroom.heart.org/news/type-2-diabetes-may-affect-heart-structure-and-increase-complications-and-death-among-heart-failure-patients-of-asian-ethnicity?preview=290cfaa82007a01fe4c338c0084aeb73

After August 21, view the manuscript online.

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Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the Association’s policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at https://www.heart.org/en/about-us/aha-financial-information.

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