Artemisinin from sweet wormwood treats not just malaria but also CANCER | 甜艾草中的青蒿素不僅可以治療瘧疾,還可以治療癌症

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Contact Dr. Lu for information about cancer treatments。聯繫盧博士,獲取有關癌症治療資訊。

Comment:  Anything that is anti-inflammatory, antiviral, anti-fungal, anti-malarial. anti-parasitic have the potential to be anticancer!!!!!!!!!!

評論:任何抗真菌、抗瘧疾的東西。 抗寄生蟲藥具有抗癌潛力!!!!!!!!!

Artemisinin from sweet wormwood treats not just malaria but also CANCER

07/05/2023 // Ethan Huff //

Slightly modified without altering messages

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A unique category of antimalarial drugs known as artemisinins, or simply artemisinin, shows promise as a novel anti-cancer therapy.   A study published in the journal Pharmacology & Therapeutics indicates that repurposing drugs for other purposes, such as artemisinin for cancer, “can drastically fasten new therapeutic discovery, ensuring greater accessibility and affordability globally.”

“Cancer is a major cause of death globally and the majority of cancer leading to deaths occur in Low and Middle Income Countries (LMICs) where conventional treatment options are often limited due to financial cost,” the study report claims.

As for artemisinins, they “have an excellent safety and tolerability profile as well as being affordable for deployment in Low and Middle Class Income Countries at around USD1 per daily dose. Robust, well designed clinical trials of artemisinin drug repurposing are indicated for a variety of different cancers and treatment settings.”

(Related: Artemisinin is also a remedy for malaria, several localized cases of which have emerged in Florida and Texas.)

Artemisinins are much safer and arguably much more effective than chemotherapy and radiation therapy which are damaging to healthy cells/tissues

Artemisinin was first isolated from sweet wormwood by eminent Chinese scientist Prof. Youyou Tu four decades ago who late won a Nobel Prize for her work on Artemisinins.  She discovered that artemisinin is a effective medication for treating malaria with an excellent safety profile.  The drug class is used globally to treat the disease.

Ever since, artemisinin and its derivatives have been explored for a series of health conditions including cancer.

Brighteon.TV

“Artemisinins are a remarkable group of compounds that have shown promising cytotoxic effects against viruses, fungi and a variety of cancers as well as powerful anti-inflammatory effects in animal models of asthma, sepsis, arthritis, pancreatitis, systemic lupus erythematosus and haemorrhagic shock,” the researchers explain, citing a range of sources to back their use for each of these unique purposes.

Although being labeled as “drugs,” artemisinins are natural (not synthesized) because they are isolated and purified from sweet wormwood (Artemisia annua L.).  They represent a family of sesquiterpene trioxane compounds containing an active metabolite known as dihydroartemisinin, or DHA for short.

“Artesunate, artemether and arteether are derivatives of artemisinin that are wholly or partially converted into the active metabolite dihydroartemisinin (DHA),” the authors say in their report.

“Sweet wormwood (qinghao) has been used in traditional Chinese medicine for thousands of years to treat fevers and a variety of inflammatory conditions. Humanity has probably wrestled with the life-threatening global epidemic of malaria since 770 BCE with a detailed description of symptoms of malaria described in the Inner Canon of the Yellow Emperor, written around the time of the Chun Qiu and Qin Dynasties (770–207 B·C.).”

Renowned Chinese physician Ge Hong (284-363) listed qinghaosu as an essential remedy for fevers in the publication Emergency Prescriptions Kept up one’s Sleeve. He also wrote a treatise called “On Airs, Waters, and Places”in 400 B.C. when Hippocrates was describing “agues” and “tertian fevers” as frequently affecting people who lived close to swamps and marshlands where mosquitoes happen to live and breed.

Fast-forward to today and artemisinins are not only being used to treat malaria but also cancer.

“The antimalarial quinine was used in the early 20th century as an anti-arrhythmic agent to treat atrial fibrillation,” the study explains.

“Difluoromethylornithine (DFMO) which was originally developed as an anti-cancer therapy has been repurposed as a treatment for sleeping sickness. To date there are over 100 candidate drugs undergoing drug repurposing clinical trials for cancer.”

“An artemisinin drug repurposing programme for a number of cancer types, with a variety of clinical settings and combination therapies from pump priming window studies to Phase III clinical trials is urgently needed.”

Looking for more information about how to deal with cancer naturally? Visit CancerSolutions.news.

Sources for this article include:

ncbi.nlm.nih.gov

NaturalNews.com

 

甜艾草中的青蒿素不僅可以治療瘧疾,還可以治療癌症

一類獨特的抗瘧藥物被稱為青蒿素,或簡稱青蒿素,顯示出作為一種新型抗癌療法的前景。

發表在《藥理學與治療學》雜誌上的研究解釋說,將藥物重新用於其他目的,例如治療癌症的青蒿素,“可以顯著縮短新的治療發現途徑,確保全球範圍內更容易獲得和負擔得起。”

該研究進一步解釋說:“癌症是全球死亡的主要原因,大多數與癌症相關的死亡發生在中低收入國家(LMIC),這些國家的傳統治療方案往往受到財務成本的限制。”

“青蒿素具有出色的安全性和耐受性,並且可以以每日 1 美元左右的劑量在中低收入國家部署。穩健、精心設計的青蒿素藥物再利用臨床試驗適用於各種不同的癌症和治療 設置。”

(相關:青蒿素也是一種治療瘧疾的藥物,佛羅里達州和德克薩斯州已經出現了幾起局部病例。)

青蒿素比化療和放療更安全,而且可以說更有效

四十年前,諾貝爾獎獲得者、中國著名科學家屠呦呦教授首先發現青蒿素是治療瘧疾的強效藥物。 世界各地都在使用該類藥物來減輕這種疾病。

從那時起,青蒿素類藥物繼續引起科學家和醫學專業人士的興趣,因為他們認識到青蒿素作為其他疾病的新型治療劑的重新利用潛力很大。

“青蒿素是一類非凡的化合物,對病毒、真菌和多種癌症具有良好的細胞毒性作用,並且在哮喘、敗血症、關節炎、胰腺炎、系統性紅斑狼瘡和失血性休克的動物模型中具有強大的抗炎作用, ”該論文解釋道,並引用了一長串消息來源來支持它們用於這些獨特目的的每一個。

請記住,儘管被標記為“藥物”,但青蒿素在技術上是天然的,因為它們是從甜艾草(Artemisia annua L.)中提取的。 它們代表了倍半萜三氧雜環己烷藥物家族,其中含有一種稱為二氫青蒿素(簡稱 DHA)的活性代謝物。

研究表明:“青蒿琥酯、蒿甲醚和蒿乙醚是青蒿素的衍生物,它們全部或部分轉化為活性代謝物二氫青蒿素 (DHA)。”

“兩千年以來,青蒿一直被用於傳統中醫治療發燒和各種炎症性疾病。早在公元前 770 年,人類就可能一直在與威脅生命的全球瘧疾流行作鬥爭,詳細描述 《黃帝內經》中描述的瘧疾症狀,成書於春秋秦時期(公元前 770-207 年)。”

著名中醫葛洪(284-363)在《袖手旁觀的急救方》中將青蒿素列為治療發燒的必備藥物。 他還在公元前 400 年寫了一篇名為《論空氣、水域和地點》的論文。 當時希波克拉底描述“瘧疾”和“三日熱”經常影響居住在蚊子恰好生活和繁殖的沼澤和沼澤地附近的人們。

快進到今天,青蒿素不僅用於治療瘧疾,還用於治療癌症。

“抗瘧藥奎寧在 20 世紀初被用作抗心律失常藥物來治療心房顫動,”該研究解釋道。

“二氟甲基鳥氨酸 (DFMO) 最初是作為一種抗癌療法而開發的,現已被重新用作昏睡病的治療方法。迄今為止,已有 100 多種候選藥物正在進行癌症藥物重新利用臨床試驗。”

“迫切需要針對多種癌症類型的青蒿素藥物再利用計劃,以及從泵啟動窗口研究到 III 期臨床試驗的各種臨床環境和聯合療法。”

 

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