Toxicity of graphene oxide in covid 19 gene therapy | 氧化石墨烯在covid 19基因治療中的毒性

The so-called covid 19 vaccines are actually gene therapy and designed to alter your genetics.  Graphene oxide is one main ingredient which is highly toxic.  It is used to carry the drugs right to the targets.  This chemical is absolutely weapon-grade chemical that damage multiple organs and it is not surprising that people die after receiving covid 19 vaccines.

所謂的 covid 19 疫苗實際上是基因療法,旨在改變您的基因。 氧化石墨烯是一種劇毒的主要成分。 它用於將藥物運送到目標。這種化學物質絕對是武器級化學物質,會損害多個器官,人們在接種 covid 19 疫苗後死亡也就不足為奇了。

REPORTS AND SCIENTIFIC PUBLICATIONS ON THE TOXICITY OF GRAPHENE OXIDE TO LIVING ORGANISMS AND TO HUMANS IN PARTICULAR

1- Graphene oxide generates thrombi: 氧化石墨烯產生血栓
https://www.researchgate.net/publication/328338305_Graphene_Oxide_Touches_Blood_In_Vi
vo_Interactions_of_Bio-Coronated_2D_Materials

2- Graphene oxide generates blood coagulation: 氧化石墨烯產生凝血作用:
https://vu2004.admin.hosting8.ing.udec.cl/Proyectos/investigacion -con-grafeno-con-
aplicaciones-hemostaticas/

3- Toxicity of graphene-family nanoparticles: a general review of the origins
and mechanisms. 石墨烯家族納米粒子的毒性:起源和機制的一般回顧。
https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989 -016- 0168-y

4- Toxicity of graphene in human sperm: 石墨烯在人類精子中的毒性:
https://francis.naukas.com/2016/08/21/toxicidad-del-grafeno-y-los-nanotubos-de-
carbono-en-el-esperma-humano/

5- The dangers of graphene and its side effects on human biology:  石墨烯的危害及其對人體生物學的副作用
https://computerhoy.com/noticias/hardware/peligros-del-grafeno-sus- efectos-
secundarios-12591

6- Graphene nanomaterials: synthesis, biocompatibility and cytotoxicity: 石墨烯納米材料:合成、生物相容性和細胞毒性:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274822/

7- Nanotoxicology: Breathing carbon nanotubes causes pulmonary fibrosis,
a cause of lung cancer: 納米毒理學:吸入碳納米管會導致肺纖維化,這是肺癌的一個原因
https://francis.naukas.com/2009/10/29/nanotoxicologia-respirar-
nanotubos-de- carbono-produce-fibrosis-pulmonar-una-causa-de-cancer-
de-pulmon/

8- Safety assessment of graphene-based materials: Focus on human
health and the environment: 石墨烯基材料的安全評估:關注人類健康和環境:
https://pubs.acs.org/doi/10.1021/acsnano.8b04758#

9- Graphene oxide is detected in the body by specialized cells of the
immune system causing the same symptomatology as the alleged
“SARSCOV2”: 免疫系統的特化細胞在體內檢測到氧化石墨烯,引起與所謂的“SARSCOV2”相同的症狀:
https://www.graphene- info.com/graphene-oxide-detected-body-specialized-cells-immune-system

10- Toxicity of graphene in normal human lung cells:  石墨烯對正常人肺細胞的毒性:
https://pubmed.ncbi.nlm.nih.gov/21485826/

11- Can nanomaterials induce reproductive toxicity in male mammals?: 納米材料能否誘導雄性哺乳動物的生殖毒性?:
https://www.sciencedirect.com/science/article/abs/pii/S0048969720378852

12- Graphene oxide affects the outcome of in vitro fertilization by interacting
with the sperm membrane in an animal model:  氧化石墨烯通過與動物模型中的精子膜相互作用來影響體外受精的結果:
https://www.sciencedirect.com/science/article/pii/S0008622317312757#undfig1

13- Effects of Nano-Graphene Oxide on Testis, Epididymis and Fertility of Wistar Rats: 納米氧化石墨烯對Wistar大鼠睾丸、附睾和生育力的影響:
https://www.researchgate.net/publication/315776736_Effects_of_Nano –
Graphene_Oxide_on_Testis_Epididymis_and_Fertility_of_Wistar_Rats

14- Graphene oxide nano-bio interaction induces inhibition of spermatogenesisand disturbance of fatty acid metabolism in the nematode Caenorhabditiselegans: 氧化石墨烯納米生物相互作用誘導線蟲秀麗隱桿線蟲精子發生抑制和脂肪酸代謝紊亂 https://pubmed.ncbi.nlm.nih.gov/30218681/

15- Graphene oxide touches blood: in vivo interactions of “bio-coronated”
2D materials: 氧化石墨烯接觸血液:“生物加冕”的體內相互作用二維材料:
https://pubs.rsc.org/en/content/articlelanding/2019/nh/c8nh00318a#!divAbstract

16- Toxicity of graphene in human sperm and consequences:  石墨烯在人類精子中的毒性和後果:
https://francis.naukas.com/2016/08/21/toxicidad-del-grafeno-y-los-nanotubos-de-carbono-en-el-esperma-humano/

17- Graphene oxide can induce in vitro and in vivo mutagenesis (cancer): 氧化石墨烯可以誘導體外和體內誘變(癌症):
https://www.nature.com/articles/srep03469

18- Repeated exposure to aerosolized graphene oxide mediates autophagy
inhibition and inflammation in a three-dimensional human airway model: 在三維人體氣道模型中反复暴露於霧化氧化石墨烯介導自噬抑制和炎症:
https://www.sciencedirect.com/science/article/pii/S2590006420300107?via%3Dihub #fig5

19- Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model: 在 3D 人肺模型中,單次暴露於氣溶膠氧化石墨烯和石墨烯納米片不會引發急性生物反應:
https://www.sciencedirect.com/science/article/pii/S0008622318304706?via%3Dihub #undfig1

20- Physico-chemical properties based on differential toxicity of graphene
oxide/reduced graphene oxide in human lung cells mediated by oxidative stress: 基於氧化應激介導的人肺細胞中氧化石墨烯/還原氧化石墨烯的差異毒性的物理化學性質:
https://www.nature.com/articles/srep39548

21- An assessment of the cytotoxic effects of graphene nanoparticles on the
epithelial cells of the human lungs:
https://journals.sagepub.com/doi/10.1177/0748233718817180

22- Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells:
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.2877

23- Toxicity of graphene oxide and multi-walled carbon nanotubes
against human cells and zebrafish:
https://link.springer.com/article/10.1007/s11426-012-4620-z

24- An in vitro cytotoxicity assessment of graphene nanosheets on alveolar cells:
https://www.sciencedirect.com/science/article/abs/pii/S0169433217335109?via%3Di hub

25- Graphene nanosheets damage the lysosomal and mitochondrial membranes
and induce the apoptosis of RBL-2H3 cells:
https://www.sciencedirect.com/science/article/abs/pii/S0048969720327467?via%3Di hub

26- Genotoxicity of graphene nanoribbons in human mesenchymal stem cells:
https://www.sciencedirect.com/science/article/abs/pii/S0008622312009499?via%3Di hub

27- Differential genotoxic and epigenotoxic effects of graphene family
nanomaterials (GFNs) in human bronchial epithelial cells:
https://www.sciencedirect.com/science/article/abs/pii/S1383571816300262?via%3Di hub

28- A closer look at the genotoxicity of graphene based materials:
https://iopscience.iop.org/article/10.1088/2515-7639/ab5844

29- DNA Melting and Genotoxicity Induced by Silver Nanoparticles and
Graphene:
https://pubs.acs.org/doi/10.1021/acs.chemrestox.5b00052

30- Hydroxylated-Graphene Quantum Dots Induce DNA Damage and Disrupt Microtubule Structure in Human Esophageal Epithelial Cells:
https://academic.oup.com/toxsci/article/164/1/339/4970755

31- Graphene oxide nanosheets induce DNA damage and activate the base
excision repair (BER) signaling pathway both in vitro and in vivo:
https://www.sciencedirect.com/science/article/abs/pii/S0045653517309517?via%3Dihub

32- Genotoxic response and damage recovery of macrophages to graphene
quantum dots:
https://www.sciencedirect.com/science/article/abs/pii/S0048969719304073?via%3Dihub

33- Can graphene quantum dots cause DNA damage in cells?:
https://pubs.rsc.org/en/content/articlelanding/2015/NR/C5NR01734C

34- Blood exposure to graphene oxide may cause anaphylactic death in non-
human primates:
https://www.sciencedirect.com/science/article/pii/S1748013220300918?via%3Dihub

35- Cellular and molecular mechanistic insight into the DNA-damaging potential of few-layer graphene in human primary endothelial cells:
https://www.sciencedirect.com/science/article/abs/pii/S1549963416000848?vi a%3Dihub

36- Impact of graphene oxide on human placental trophoblast viability,
functionality and barrier integrity:
https://iopscience.iop.org/article/10.1088/2053-1583/aab9e2

37- PEGylation of Reduced Graphene Oxide Induces Toxicity in Cells of the Blood–Brain Barrier: An in Vitro and in Vivo Study:
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.6b00696

38- Oxygen content-related DNA damage of graphene oxide on human retinal pigment epithelium cells:
https://link.springer.com/article/10.1007%2Fs10856-021-06491-0

39- Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells:
https://pubs.acs.org/doi/10.1021/nn1007176

40- Evaluation of Graphene Oxide Induced Cellular Toxicity and Transcriptome Analysis in Human Embryonic Kidney Cells:
https://www.mdpi.com/2079-4991/9/7/969

41- Toxicology Study of Single-walled Carbon Nanotubes and Reduced Graphene Oxide in Human Sperm:
https://www.nature.com/articles/srep30270

42- Dose-dependent effects of nanoscale graphene oxide on reproduction
capability of mammals: https://www.sciencedirect.com/science/article/abs/pii/S0008622315301366?via%3Dihub

43- Short-term in vivo exposure to graphene oxide can cause damage to the gut and testis: https://www.sciencedirect.com/science/article/abs/pii/S0304389417300171?via%3Dihub

44- Cyto and genotoxicities of graphene oxide and reduced graphene oxide
sheets on spermatozoa:
https://pubs.rsc.org/en/content/articlelanding/2014/RA/c4ra01047g

45- Nanotoxicity of Graphene and Graphene Oxide:
https://pubs.acs.org/doi/10.1021/tx400385x

46- Graphene toxicity as a double-edged sword of risks and exploitable
opportunities: a critical analysis of the most recent trends and
developments.

https://iopscience.iop.org/article/10.1088/2053-1583/aa5476

47- A differential effect of graphene oxide on the production of proinflammatory cytokines by murine microglia:
https://www.worldscientific.com/doi/abs/10.1142/S1682648515500110

48- Graphene oxide disrupted mitochondrial homeostasis through inducing
intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells:
https://www.sciencedirect.com/science/article/pii/S0304389421011225?via%3Dihub

49- Biodistribution and pulmonary toxicity of intratracheally instilled graphene oxide in mice:
https://www.nature.com/articles/am20137

50- A review of toxicity studies on graphene-based nanomaterials in laboratory animals: https://www.sciencedirect.com/science/article/abs/pii/S0273230017300119?via%3Dihub

51- Neutrophils degrade graphene oxide, mediated by myeloperoxidase:
https://www.researchgate.net/publication/351888431_Neutrophils_Defensively_Degr ade_Gra
phene_Oxide_in_a_Lateral_Dimension_Dependent_Manner_through_Two_Distinct_Myeloperoxidase_Mediated_Mechanisms

52- Dose ranging, expanded acute toxicity and safety pharmacology studies for intravenously administered functionalized graphene nanoparticle
formulations: http://europepmc.org/article/MED/24854092

53- Remote control of the cardiac activity of a living being using graphene:
https://www.infosalus.com/asistencia/noticia-manejan-celulas- cardiacas-cultivadas-
laboratorio-control-remoto-20180522073436.html

54- Graphene oxide induces apoptotic cell death in endothelial cells by
activating autophagy via calcium-dependent phosphorylation of c-Jun N-terminal kinases:
https://www.sciencedirect.com/science/article/abs/pii/S1742706116304810

55- Cellular and molecular mechanistic insight into the DNA-damaging potential of few-layer graphene in human primary endothelial
cells: https://www.sciencedirect.com/science/article/abs/pii/S1549963416000848

56- Toxicity Evaluation of Graphene Oxide in Kidneys of Sprague-Dawley Rats:
https://pubmed.ncbi.nlm.nih.gov/27043588/

57- Toxicology of carbon nanotubes and fullerenes:
https://copro.com.ar/Toxicologia_de_los_fullerenos.html

58- The Puzzling Potential of Carbon Nanomaterials: General Properties,
Application, and Toxicity:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466546/

59- Synthesis and Toxicity of Graphene Oxide Nanoparticles: A Literature Review of In Vitro and In Vivo studies:
https://www.hindawi.com/journals/bmri/2021/5518999/

60- Radio-frequency characteristics of graphene oxide:
https://aip.scitation.org/doi/abs/10.1063/1.3506468

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