Aug 26, 2022 It has always been believed that with the increase of age, the NAD+ content in the human body decreases significantly. In middle-aged and old age, the NAD+ content in the human body is only a quarter of the original, resulting in human dysfunction, including: memory decline , hair loss, poor sleep quality, decreased energy, and a series of symptoms of aging. Recently, some scientists have disputed this, arguing that the decline of NAD+ with age is not a general truth but misleading? At the same time, it is also considered unnecessary to supplement NMN or NR. A review article was published in the Journal of Nutrition in January. They summarized a series of studies reporting changes in NAD+ levels with aging in different species, including humans. I will share the highlights of this review article and my personal opinion on whether NMN needs to be supplemented. Then, I’ll introduce a new report on the new discovery that fasting increases mitochondrial NAD+ levels, and why it’s important. Finally, I would like to share with you that NMN supplementation provides a new way to treat and prevent age-related macular degeneration and retinitis.
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