健康的生活方式可减少疾病,死亡的风险 Healthy lifestyle reduces risk of disease, death

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News Release 11-Mar-2020

More time living in better cardiovascular health may lower risk of chronic diseases, mortality

Boston University School of Medicine

(Boston)–The longer you lead a healthy lifestyle during midlife, the less likely you are to develop certain diseases in later life.

The more time a person doesn’t smoke, eats healthy, exercises regularly, maintains healthy blood pressure, blood sugar and cholesterol levels and maintains a normal weight, the less likely they are to develop diseases such as hypertension, diabetes, chronic kidney disease and cardiovascular disease or to die during early adulthood.

The American Heart Association (AHA) had recommended a renewed focus on prevention to reduce the development of risk factors for cardiovascular disease (CVD) as part of its 2020 Impact Goal to improve population cardiovascular health (CVH) by 20 percent and reduce CVD mortality by 20 percent. While unhealthy lifestyle behaviors are associated with higher risks for certain diseases and death, the association of the duration in which people maintain a healthy lifestyle with the risk of disease and death had not yet been studied.

Using data from the Framingham Heart Study (FHS), researchers from Boston University School of Medicine observed participants for approximately 16 years and assessed the development of disease or death. They found that for each five-year period that participants had intermediate or ideal cardiovascular health, they were 33 percent less likely to develop hypertension, approximately 25 percent less likely to develop diabetes, chronic kidney disease and cardiovascular disease, and 14 percent less likely to die compared to individuals in poor cardiovascular health.

“Our results indicate that living a longer period of time in adulthood with better cardiovascular health may be potentially beneficial, regardless of age. Overall, our findings underscore the importance of promoting healthy behaviors throughout the life-course,” explained corresponding author Vanessa Xanthakis, PhD, FAHA, assistant professor of medicine at BUSM and Investigator for FHS.

The researchers hope this study will help people understand the importance of achieving an ideal cardiovascular health early in life and motivate them to maintain a healthy lifestyle. “On the community-level, this will overall help reduce morbidity and mortality associated with diseases such as hypertension, diabetes, chronic kidney disease and death during late adulthood.”

These findings appear online in the journal JAMA Cardiology.

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Funding for this study was provided by the National Heart, Lung, and Blood Institute’s Framingham Heart Study (contract no. N01-HC-25195 and HHSN268201500001I) and by T32-HL-125232.

(波士顿)–您在中年过上健康的生活方式的时间越长,在以后的生活中患某些疾病的可能性就越小。

一个人不吸烟,饮食健康,规律运动,保持健康的血压,血糖和胆固醇水平并保持正常体重的时间越长,患高血压,糖尿病,慢性肾脏疾病和心血管疾病或成年初期死亡。

美国心脏协会(AHA)建议重新关注预防,以减少心血管疾病(CVD)的危险因素的发展,并将其作为2020影响目标的一部分,以将人口心血管健康(CVH)改善20%,并降低CVD死亡率20%。虽然不健康的生活方式行为与某些疾病和死亡的较高风险相关,但尚未研究人们维持健康的生活方式的持续时间与疾病和死亡的风险之间的关系。

波士顿大学医学院的研究人员使用弗雷明汉心脏研究(FHS)的数据观察了参与者约16年,并评估了疾病或死亡的发生。他们发现,在参与者具有中等或理想心血管健康的每五年期间,他们患高血压的可能性降低33%,患糖尿病,慢性肾脏疾病和心血管疾病的可能性降低约25%,患高血压的可能性降低14%。与心血管健康状况较差的人相比死亡。

“我们的结果表明,无论年龄大小,成年后在心血管健康状况良好的环境中长期生活可能都是有益的。总的来说,我们的发现强调了在整个生命过程中促进健康行为的重要性。”通讯作者,美国联邦卫生事务管理局(FAHA)医学助理教授,FHS研究人员Vanessa Xanthakis博士解释说。

研究人员希望这项研究能够帮助人们了解在生命早期实现理想的心血管健康的重要性,并激发他们保持健康的生活方式。 “在社区一级,这将总体上帮助降低与高血压,糖尿病,慢性肾脏病和成年后期死亡等疾病相关的发病率和死亡率。”

这些发现在线发表在《 JAMA心脏病学》杂志上。

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