Nutritional supplementation in the treatment of chronic lymphocytic leukemia – a case report | 营养补充剂治疗慢性淋巴细胞性白血病 – 病例报告

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09/14/2017 (jkzx.com) – This is a story about a man with chronic lymphocytic leukemia. He never used chemotherapy, did not have a bone marrow transplant, and used only diet therapy to achieve long-term remission. He was diagnosed with the disease in September 1991 and was still healthy at the age of 52 when the case report was published.

Twenty years after his diagnosis, he uses his own diet. He is in good health, except that he has experienced two risk events related to chronic lymphocytic leukemia during this time period. He was recommended to take some chemotherapy drugs to overcome the symptoms of the incident, but he refused to take them and instead modified his diet regimen.

In the second incident, his methods did not seem to control his condition very well. He consulted doctors for their opinion. The doctor prescribed some additional nutritional supplements. Finally, he overcame the challenge of the second event and achieved complete molecular remission.

At the age of 28 (September 1991), the man developed massive splenomegaly, mild anemia, and thrombocytopenia. At the same time, the white blood cell count was 5700/uL, and the 61% lymphocyte and platelet count were 105,000/uL. He underwent a splenectomy in November 1991.

The patient started using his own diet program since 1993 (30 years old). He follows a vegetarian diet, occasionally using some seafood. He uses filtered water, common nutritional supplements, and exercise (mainly endurance training such as aerobic activity and walking). He avoids processed foods and uses only organic or pesticide-free foods whenever possible.

Until May 2003, the 39-year-old patient experienced fever, malaise, night sweats, and fatigue associated with chronic lymphocytic leukemia. He was diagnosed with hemolytic anemia. At this point, lab results show that 90 to 100 percent of the bone marrow has been replaced by lymphocytes. Doctors suggested steroids, rituximab, and cytotoxic chemotherapy drugs.

The patient refused to use it. Instead, he modified his dietary supplement regimen to include conjugated linoleic acid. Whey Protein with Lactoferrin and Artemisinin Plant Extract. Even though he feels bad, he still insists on walking and swimming every day.

Five months later in October 2003, the hemoglobin normalized and the symptoms abated. The patient made a full recovery.

In May 2006, at the age of 42, he underwent a bone marrow biopsy. Results showed that lymphocyte replacement was increased to 30%. In December 2009, the white blood cell count was 17,500/μL and the lymphocytosis was 63%. At age 46, the patient consulted his physician. Based on previous research, a doctor recommended a recipe consisting of reishi mushrooms, chaga mushroom, and green tea. This formula provides 1200 mg of the most abundant epigallocatechin-3-gallate (EGCG) found in green tea.

He also assessed his resistance to cancer progression by testing a range of factors. The doctor found that the glucose metabolism was abnormal, and the vitamin D in the blood (46.7 ng/mL) was slightly below the optimal level (50~70 ng/mL). Therefore, the doctor added 10.8 grams of fish oil containing eicosapentaenoic acid and 2.4 grams of docosahexaenoic acid per day, 4 grams of curcumin, vitamin D3, skullcap and probiotics per day. Calcium and magnesium are also added to enhance bone density.

In October 2010, the white blood cell count reached 47,88/uL, and the lymphocytes were 81.6%. In December 2010, the dose of EGCG was increased to 4 grams per day. In February 2011, the white blood cells reached 60,600/uL and the lymphocytes were 84%. Other factors looked fine except vitamin D levels which were too high (110ng/mL). Therefore, vitamin D supplementation was cut back.

In March 2011, the white blood cell count dropped to 30,600/uL. By August 2011, the count was 6800/uL and the lymphocytes were 49%. Laboratory results did not show any signs of lymphoproliferative disease.

Again in September 2014, at the age of 51, flow cytometry of a second aspirate did not show any evidence of lymphoproliferative disease. The IgVH mutation was also found to be absent.

At the age of 52 in 2015, the patient is still alive and well. He takes 1.2 grams of EGCG per day and sticks to his dietary lifestyle.

Comment: While EGCG may have played a role in the chronic lymphocytic leukemia patient’s remission, his doctor and the supplements he had been using appeared to be important to his recovery. Other therapies are now known to treat chronic lymphocytic leukemia. The effect is also very good.

Assuming he uses chemotherapy as his doctor recommends, he will not achieve remission. Maybe long dead. This case report shows that your own dietary regimen may not always be the best, but it can be helpful for your condition. On the other hand, you probably already know that chemotherapy drugs can kill patients quickly, even if the disease is under control, patients can pass away from the damage to the body. (Dr. Lu)

 

09/14/2017 (jkzx.com) – 这是一个有关患有慢性淋巴细胞性白血病(chronic lymphocytic leukemia)男子的故事。他从来没有使用化疗,没有骨髓移植,仅使用饮食疗法来实现长期缓解。他于1991年9月被诊断患有该病,在病例报告发表时,他52岁依然健康。

诊断二十年后,他使用自己的饮食疗法。他健康状况良好,除了他在这段时间内经历了与慢性淋巴细胞白血病有关的两个风险事件。他被推荐采取一些化疗药物来克服事件发生的症状,但他拒绝服用,而是修改他的饮食方案。

在第二次事件中,他的方法似乎没有很好控制他的病情。他咨询了医生获得他们的意见。医生开了一些额外的营养补品。最后,他克服了第二次事件的挑战,实现了完全分子水平的缓解。

该男子在28岁时(1991年9月)出现大量脾肿大,轻度贫血和血小板减少症。同时白血细胞计数为5700 / uL,61%淋巴细胞和血小板计数为105,000 / uL。他于1991年11月接受了脾切除术。

患者自1993年起(30岁)开始使用自己的饮食方案。他遵循素食饮食,偶尔使用一些海鲜。他使用过滤水,常见的营养补充剂和运动(主要是耐力训练,如有氧活动和行走)。他避免加工食品,只要有可能,就只使用有机或无农药食品。

直到2003年5月,39岁的患者经历了与慢性淋巴细胞性白血病有关的发烧,不适,盗汗和疲劳的事情。他被诊断患有溶血性贫血。此时,实验室结果显示90〜100%的骨髓被淋巴细胞所取代。医生建议使用类固醇,利妥昔单抗和细胞毒性化疗药物。

病人拒绝使用。相反,他修改了他的饮食补充方案,以包括共轭亚油酸。乳清蛋白与乳铁蛋白和青蒿素植物提取物。即使感觉很差,他仍然坚持每天走路和游泳。

五月后于2003年10月,血红蛋白正常化,症状减轻。患者完全康复了。

2006年5月,在42岁时,他进行了骨髓活检。结果表明,淋巴细胞置换增加至30%。 2009年12月,白细胞计数为17,500 /μL,淋巴细胞增多为63%。 46岁时,病人咨询了他的医生。根据以前的研究,一位医生推荐了由reishi菇,chaga mushroom和绿茶组成的配方。该配方提供1200毫克绿茶中最丰富的表没食子儿茶素-3-没食子酸酯(EGCG)。

他还通过测试一系列因素评估了他对癌症进展的抵抗能力。医生发现葡萄糖代谢异常,血液中维生素D(46.7 ng / mL)略低于最佳水平(50〜70 ng / mL)。因此,医生每天加入10.8克含有二十碳五烯酸的鱼油和2.4克二十二碳六烯酸,每天4克姜黄素,维生素D3,黄芩和益生菌。还加入钙和镁以增强骨密度。

2010年10月,白细胞计数达到47,88 / uL,淋巴细胞为81.6%。 2010年12月,EGCG的剂量每天增加到4克。 2011年2月,白细胞达到60,600 / uL,淋巴细胞为84%。除维生素D水平过高(110ng / mL)外,其他因素看起来很好。因此,维生素D补充被削减。

2011年3月,白细胞计数降至30,600 / uL。到2011年8月,计数为6800 / uL,淋巴细胞为49%。实验室结果没有显示淋巴增生性疾病的任何迹象。

再次在2014年9月,在51岁时,第二次抽吸液的流式细胞术没有显示淋巴组织增生性疾病的任何证据。发现IgVH突变也不复存在。

在2015年的52岁时,患者仍然健康活着。他每天服用1.2克EGCG,并坚持自己的饮食生活方式。

评论:虽然EGCG可能在慢性淋巴细胞性白血病患者缓解中发挥作用,但他的医生和他一直使用的补充剂对他的康复似乎很重要。现在已知其它的一些疗法也可以用来治疗慢性淋巴细胞性白血病。效果也是很好。

假设他按医生的建议使用化疗,他不会达到缓解。也许早就过世了。这个案例报告表明,你自己的饮食疗法可能不总是最好的,但对你的病情是有帮助的。另一方面,你或许已经知道化疗药物可以快速杀死患者, 哪怕病情已经得到控制,病人可以因为身体受的伤害过世。(陆博士)

 

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