Diet rich in animal foods, alcohol and sugar linked to ‘inflammatory’ gut microbiome 富含動物性食物,酒精和糖的飲食與“炎症”腸道微生物組有關

中文版谷歌中文翻譯(90% 準確率) | English translation
Buy/Sell Your Domains Here。在這裡購買/出售您的域名
Contact Dr. Lu for information about cancer treatments。聯繫盧博士,獲取有關癌症治療資訊。

News Release 13-Apr-2021

Editor’s note: This may be why a plant-based diet can reduce risk of all sorts of diseases including cancer, diabetes, heart disease, stroke, depression, and other chronic diseases. This also explains why animal meat, alcohol and sugar are associated with elevated risk of cancer and other chronic diseases.

Dr. Gerson who advocated Gerson diet, which is largely a vegetarian diet found that cancer patients fare worse when they eat even a tiny bit of animal meat. Some patients may think that they need to animal meat to help them recover from conventional therapies. That thought can be fatal. Many patients who tried this or that natural therapy but could not experience any reduction in tumor size or improvement of their condition, probably because they use some animal-derived foods! Most of cancer patients if not 100% would be better off eating a plant-based diet and avoiding animal meat completely.

編者註:這也許就是為什麼以植物為基礎的飲食可以降低各種疾病風險的原因,包括癌症,糖尿病,心髒病,中風,抑鬱症和其他慢性疾病。 這也解釋了為什麼動物肉,酒精和糖與癌症和其他慢性疾病的風險升高相關。

提倡Gerson飲食(主要是素食)的Gerson博士發現,即使只吃一點動物肉,癌症患者的病情也會惡化。 一些患者可能認為他們需要動物肉以幫助他們從常規療法中康復。 這種想法可能是致命的。 許多嘗試過這種或那種自然療法但沒有經歷任何腫瘤縮小或病情改善的患者,可能是因為他們使用了一些動物性食物! 如果不是100%,大多數癌症患者最好吃以植物為主的飲食,並完全避免食用動物肉。

But high intake of plant-based foods linked to ‘friendly’ anti-inflammatory microbes

BMJ

Research News

A high dietary intake of animal products, processed foods, alcohol and sugar is linked to a gut microbiome that encourages inflammation, finds research published online in the journal Gut.

But a diet rich in plant-based foods is linked to gut microbes that have the opposite effect, the findings show, prompting the researchers to suggest that dietary modifications may help to ease inflammation in the body.

The variety and volume of bacteria in the gut, known as the microbiome, directly affects the balance of pro- and anti-inflammatory responses in the gut.

This ecosystem also affects systemic immunity and an imbalance is implicated in a growing number of inflammatory conditions, ranging from diabetes to arthritis, heart disease and systemic lupus erythematosus, note the researchers.

But it’s still not clear if specific foods and dietary patterns might affect the composition of the gut microbiome and consequently inflammatory responses in the gut.

To try and find out, the researchers looked at the interplay between usual diet, gut microbes, and intestinal inflammation in 1425 people with either inflammatory bowel disease (Crohn’s disease or ulcerative colitis; 331); irritable bowel syndrome (223); or a normal gut (871).

Each person provided a stool sample for microbial analysis and filled in a Food Frequency Questionnaire (FFQ) to quantify average daily nutrient intake. Specific food items were aggregated into 25 food groups measured in grams per day.

Analysis of the data revealed 38 associations between dietary intake and particular bacterial clusters. What’s more, 61 individual foods and nutrients were associated with 61 species of bacteria and 249 metabolic processes across all the study participants.

Processed foods and animal-derived foods were consistently associated with a higher relative volume of ‘opportunistic’ bacterial species, including certain bacteria belonging to Firmicutes and Ruminococcus sp, and involved pro-inflammatory activity.

Plant foods and fish, on the other hand, were associated with ‘friendly’ bacterial species involved in anti-inflammatory activity.

Eating nuts, oily fish, fruit, vegetables and cereals was linked to a higher abundance of bacteria, such as Faecalibacterium sp which produce short chain fatty acids: these acids help control inflammation and protect the integrity of the cells lining the gut.

Red wine was similarly associated with a higher abundance of several bacteria producing short chain fatty acids. But total alcohol intake, spirits, and sugar were associated with friendly microbial species and functions.

Coffee intake was also associated with a higher relative abundance of Oscillibacter sp, while fermented dairy products, such as buttermilk and yoghurt were strongly associated with anti-inflammatory bacteria, such as Bifidobacterium, Lactobacillus, and Enterococcus sp.

Food clusters of breads; legumes, such as lentils, peas, and chickpeas; fish; and nuts were consistently associated with a lower relative abundance of ‘opportunistic’ bacteria and pro-inflammatory activity.

But a fast food cluster of meats, french fries, mayonnaise and soft drinks was associated with a cluster of ‘unfriendly’ Clostridium bolteae, Coprobacillus and Lachnospiraceae bacteria across all study participants.

In the absence of fibre, these bacteria turn to the mucus layer of the gut to feed off, leading to an erosion of the integrity of the gut, note the researchers.

These patterns were observed across all groups of study participants, suggesting overlaps in diet and gut microbiome signalling between healthy people and those with inflammatory bowel disease or irritable bowel syndrome, suggest the researchers.

This is an observational study, and as such, can’t establish cause, added to which it’s not clear how long it takes for gut bacteria to respond to dietary changes, caution the researchers.

But they write: “Despite these limitations, we were able to derive dietary patterns that consistently correlate with groups of bacteria and functions known to infer mucosal protection and anti-inflammatory effects.

“The findings suggest shared responses of the gut microbiota to the diet across patients with [Crohn’s disease, ulcerative colitis, irritable bowel syndrome] and the general population that may be relevant to other disease contexts in which inflammation, gut microbial changes, and nutrition are a common thread.”

And they conclude: “Long-term diets enriched in legumes, vegetables, fruits and nuts; a higher intake of plant over animal foods with a preference for low-fat fermented dairy and fish; while avoiding strong alcoholic drinks, processed high-fat meat and soft drinks, have a potential to prevent intestinal inflammatory processes via the gut microbiome.”

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Externally peer reviewed? Yes
Evidence type: Observational
Subjects: People

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