人造二氧化硅纳米粒子诱发炎症 Man-made silica nanaparticles induce inflammation

A study published on https://www.sciencedirect.com/science/article/abs/pii/S0378427408012952 suggests that ingestion of man-made silica or silicon dioxide can induces the generation of reactive oxygen species (ROS) and inflammation both in vivo and in vitro.

It is commonly believed ROS promotes or speed up the aging process. These dangerous ROS can also cause cellular injury leading to chronic diseases like cancer.

Yet, silica nanoparticles are very commonly used in dietary supplements and processed foods as a flow agent or dispersing agent or white color enhancer.

Silica is added in dietary supplements and processed foods in an amount of no more than 2%. Some manufacturers may use it without disclosing it on the ingredient list or the nutrition label. This has been proved in a survey.

Early studies have proved that nanoparticles regardless of their chemical composition. Zinc oxide, titanium dioxide, silicon dioxide (or simply silica) all can travel to various organs including the brain, the liver and the kidney and cause damage to DNA because of their rigid construction.

Nanoparticles can disrupt DNA and cause mutations which if unfortunately enough can lead to a process called carcinogenesis, cancer causing process.

Titanium dioxide has been taken out from many supplements because they realize that this type of nanoparticles can be detrimental. But all sorts of nanoparticles act similarly. Silica is no exception.

1447/5000在https://www.sciencedirect.com/science/article/abs/pii/S0378427408012952上發布的一項研究表明，攝入人造二氧化矽或二氧化矽可以在體內誘導活性氧（ROS）的產生和炎症和體外。

通常認為ROS可以促進或加速老化過程。這些危險的ROS也可能導致細胞損傷，導致癌症等慢性疾病。

然而，二氧化矽納米顆粒非常普遍地用作膳食補充劑和加工食品中的流動劑或分散劑或白色增色劑。

膳食補充劑和加工食品中添加的二氧化矽含量不得超過2％。一些製造商可能會在未將其公開在成分錶或營養標籤上的情況下使用它。一項調查已經證明了這一點。

早期的研究證明，納米粒子無論其化學成分如何。氧化鋅，二氧化鈦，二氧化矽（或簡稱二氧化矽）都可以傳播到包括大腦，肝臟和腎臟在內的各種器官，並且由於其剛性結構而對DNA造成損害。

納米粒子會破壞DNA並引起突變，如果不幸的話，這些突變會導致稱為癌變的過程，即致癌過程。

二氧化鈦已從許多補品中取出，因為他們意識到這種類型的納米顆粒可能有害。但是各種納米粒子的作用都相似。二氧化矽也不例外。

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