健康的饮食习惯可能有助于预防肾脏疾病 A healthy diet may help prevent kidney disease

根据已发表研究的分析,保持健康饮食可能有助于预防肾脏疾病。研究结果发表在即将发行的CJASN中。

饮食结构的改变可以帮助延缓慢性肾脏病(CKD)的进程,但是尚不清楚健康的饮食是否可以预防这种疾病的发展。为了进行调查,卡特里娜·巴赫(澳大利亚邦德大学)的Jaimon Kelly博士及其同事分析了截至2019年2月发布的所有相关研究。

分析包括18项研究,共有630,108名成年人接受了平均10.4年的随访。健康的饮食习惯通常会鼓励摄入更多的蔬菜,水果,豆类,坚果,全谷类,鱼类和低脂乳制品,并减少摄入红色和加工肉类,钠和含糖饮料。

健康的饮食习惯可使CKD发生率降低30%。它还与白蛋白尿发生率降低23%有关,白蛋白尿是肾脏损害的早期指标。

NEWS RELEASE 

A healthy diet may help prevent kidney disease

Analysis of published studies uncovers link

AMERICAN SOCIETY OF NEPHROLOGY

Highlights

  • In an analysis of published studies, a healthy dietary pattern was associated with a 30% lower incidence of chronic kidney disease.
  • A healthy dietary pattern was also linked with a 23% lower incidence of albuminuria, an early indicator of kidney damage.

Washington, DC (September 24, 2019) — Maintaining a healthy diet may help prevent kidney disease, according to an analysis of published studies. The findings appear in an upcoming issue of CJASN.

Making dietary changes can help slow the progression of chronic kidney disease (CKD), but it’s not clear whether a healthy diet is protective against the development of the disease. To investigate, Jaimon Kelly, PhD, Katrina Bach (Bond University, Australia), and their colleagues analyzed all relevant studies published through February 2019.

The analysis included 18 studies with a total of 630,108 adults who were followed for an average of 10.4 years. Healthy dietary patterns typically encouraged higher intakes of vegetables, fruit, legumes, nuts, whole grains, fish, and low-fat dairy, and lower intakes of red and processed meats, sodium, and sugar-sweetened beverages.

A healthy dietary pattern was associated with a 30% lower incidence of CKD. It was also linked with a 23% lower incidence of albuminuria, an early indicator of kidney damage.

“These results add to the accumulating evidence base supporting the potential benefit of adhering to a healthy dietary pattern–such as the Mediterranean, DASH diet, or National Dietary Guidelines–and the primary prevention of chronic conditions, including type 2 diabetes, cardiovascular disease, cognitive decline, cancer, and all-cause mortality,” said Dr. Kelly. “These results may assist in developing public health prevention programs for CKD, which may assist in reducing the burden of the disease.” Dr. Kelly noted that dietary approaches to kidney health that target individual (or multiple) nutrients can be difficult, but focusing on whole foods rather than nutrients can make it easier for clinicians to educate patients and easier for patients to carry out.

“Randomized clinical trials with sufficient follow-up time to ascertain meaningful kidney outcomes are necessary to determine whether a change in dietary patterns is causally related to favorable kidney health outcomes,” wrote the authors of an accompanying editorial. “Meanwhile, there may be sufficient observational evidence for clinicians to emphasize the importance of healthy dietary patterns to individuals who are healthy or who are at risk of developing CKD.”

An accompanying Patient Voice editorial notes the importance of including children in future studies.

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Study co-authors include Suetonia Palmer, PhD, Giovanni Strippoli MD, PhD, and Katrina Campbell, PhD.

Disclosures: The authors reported no conflicts of interest.

The article, entitled “Healthy Dietary Patterns and Incidence of Chronic Kidney Disease: A Meta-Analysis of Cohort Studies,” will appear online at http://cjasn.asnjournals.org/ on September 24, 2019, doi: 10.2215/CJN.00530119.

The editorial, entitled “Can Dietary Patterns Modify Risk for CKD?” will appear online at http://cjasn.asnjournals.org/ on September 24, 2019, doi: 10.2215/CJN.09440819.

The Patient Voice editorial, entitled “Diet Patterns and Kidney Disease,” will appear online at http://cjasn.asnjournals.org/ on September 24, 2019, doi: 10.2215/CJN.09660819.

Since 1966, ASN has been leading the fight to prevent, treat, and cure kidney diseases throughout the world by educating health professionals and scientists, advancing research and innovation, communicating new knowledge, and advocating for the highest quality care for patients. ASN has more than 20,000 members representing 131 countries. For more information, please visit http://www.asn-online.org or contact the society at 202-640-4660.

The content of this news release is solely the responsibility of the authors and does not necessarily represent the official views or imply endorsement of the National Institutes of Health.

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