Crude luteolin extract against early breast cancer | 番木犀草粗提取物对抗早期乳腺癌

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Crude luteolin extract against early breast cancer

A crude extract of luteolin from some sources may be potent enough to help fight early-stage breast cancer, a new study suggests.

The authors of this study tested 19 crude tomato plant extract samples and identified the one that was most effective against breast cancer cells in vivo. The selected extracts were then tested in mice with induced 4T1 breast cancers or tumors to see how they helped the tumors.

Studies have shown that selected crude extracts of custard apple are able to reduce tumor size and weight, prevent metastasis and induce apoptosis in 4T1 breast cancer cells both in vitro and in vitro.

The study also revealed that the extract increased the concentration of white blood cells, T cells and natural killer cells, which are thought to be important in the fight against various cancer cells.

Three breast cancer cell lines were tested, MCF-7, MDA-MB-231 and 4T1. But in vivo testing was only performed with selected extracts in mice with 4 T1 mammary tumors. It is still not known whether these extracts are also effective in other types of breast cancer.

The authors suggest that the preparation of the crude extract of luteolin is also important in determining the efficacy of the treatment on breast cancer cells. (David Liu)

 

番木犀草粗提取物对抗早期乳腺癌

一项新的研究表明,来自一些地方的番木犀草粗提取物可能足够有力以帮助对抗早期乳腺癌。

本研究的作者测试了19种番茄植物粗提取物样品,并鉴定了对体内乳腺癌细胞最有效的一种。然后在具有诱导的4T1乳腺癌或肿瘤的小鼠中测试所选的提取物,以观察其如何有助于肿瘤。

研究表明,所选的番荔枝粗提物能够在体外和体外4T1乳腺癌细胞中减少肿瘤的大小和重量,防止转移和诱导细胞凋亡。

该研究还揭示了该提取物增加了白细胞,t细胞和自然杀伤细胞的浓度,这被认为对于各种癌细胞的搏斗是重要的。

测试了三种乳腺癌细胞系,MCF-7,MDA-MB-231和4T1。但是体内测试仅在具有4个T1乳腺肿瘤的小鼠中使用选择的提取物进行。仍然不知道这些提取物是否也在其他类型的乳腺癌中也有效。

作者提出,番木犀草粗提取物的制备在确定对乳腺癌细胞的治疗效力中也是重要的。 (David Liu)

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