Phytotherapy and Nutritional Supplements on Breast Cancer 用于乳腺癌治疗的植物疗法和营养补充剂

中文版谷歌中文翻譯(90% 準確率) | English translation
Buy/Sell Your Domains Here。在這裡購買/出售您的域名
Contact Dr. Lu for information about cancer treatments。聯繫盧博士,獲取有關癌症治療資訊。

5. Conclusions and Perspectives

Breast cancer is one of the most leading causes of cancer death among women. Women with a breast cancer history often resort to alternative and complementary therapies, mainly phytotherapeutic products and nutritional supplements, for the management of the typical symptoms and adverse effects of conventional cancer treatments. Although extensively used, these products are poorly regulated and can have either positive (e.g., synergetic effects) or negative (e.g., metabolic and drug interactions, diminishing the therapeutic benefits of conventional cancer treatments). There is a lack of high-quality scientific evidence for many of the most phytotherapeutic products and nutritional supplements and more clinical scientific evidences concerning the safety and efficacy are mandatory. Additionally, pharmacovigilance practices for these natural products are crucial to understanding the benefit, limitations, dosage regimen, and potential effects and how these modalities need to be modified during some periods.

Tables 1 and 2 summarize the main effects in the consulted clinical studies. Clinical studies were gathered accordingly to disease phase and main action. The ratio of trials versus nontrials included all the interventional clinical trials versus total of clinical studies.

Table 1: The main clinical effects of the most common phytotherapeutic products used in breast cancer.
Table 2: The main clinical effects of the most common nutritional supplements used in breast cancer.

Based on clinical study data, the following supplements can be used in the different phases of breast cancer history:

(i) Preventive EffectsPhytotherapeutic products: flaxseed; green tea.Nutritional supplements: omega 3 polyunsaturated fatty acids (minimum daily dose of 2.5 g in women at high breast cancer risk).

(ii) During Conventional Treatments after DiagnosisPhytotherapeutic products: U. tomentosa as an adjuvant treatment of FAC (Fluorouracil, Doxorubicin, and Cyclophosphamide) regimen in Invasive Ductal Carcinoma Stage II; Curcuma longa as coadjuvant in docetaxel therapy; green tea as adjuvant of radiotherapy; Viscum album in side effects, recurrence, and antitumour activity.Nutritional supplements: vitamin C 500 mg + vitamin E 400 mg in side effects chemotherapy, vitamin D (necessary doses to target 30–50 ng/ml serum levels) + calcium, and vitamin D as adjuvant of aromatase inhibitor therapy; DHA as adjuvant in chemotherapy and side effects.

(iii) Posttreatment (i.e., Survival Period)Phytotherapeutic products: Salvia sp. associated with Coriolus versicolor improves immunologic function.Based on the current literature we concluded that well-designed clinical studies are needed to obtain high level of evidence to accomplish recommendation guidelines.

Conflicts of Interest

The authors declare that there are no conflicts of interest regarding the publication of this article.

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刘 大卫

Trust God, not sinful people. Worship God, but not things/people. Let God lead you, but not let others lead you. 相信上帝,而不是有罪的人。 敬拜神,而不是事/人。 讓上帝帶領你,但不要讓別人帶領你。

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