Asparaginase helps fight leukemia 33/5000 天冬酰胺酶有助于抵抗白血病

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This is an old study published in 1967.  The study examines how asparaginase which deplete asparagine, a critical amino acid, help fight leukemia in three patients.

In two patients with advanced acute lymphatic leukemia, the therapy with the enzyme L-asparaginase improved their conditions significantly.

In the third case, the patient used a large dose of the enzyme and his condition responded well.  The treatments resulted in rapid necrosis of lymph node masses and clearance of kleukemine infiltrate.

This enzyme may also help cancers like acute and chronic granulocytic leukemia.

这是1967年发表的一项古老研究。这项研究检查了耗尽三聚天冬氨酸(一种重要氨基酸)的天冬酰胺酶如何帮助对抗三名患者的白血病。

在两名患有急性急性淋巴白血病的患者中,L-天冬酰胺酶酶的治疗显着改善了他们的病情。

在第三种情况下,患者使用了大剂量的酶,他的病情反应良好。 这些治疗导致淋巴结肿块迅速坏死并清除了克雷克明。

这种酶还可以帮助治疗急性和慢性粒细胞白血病等癌症。

November 27, 1967

L-Asparaginase Therapy for Leukemia and Other Malignant Neoplasms Remission in Human Leukemia

Joseph M. Hill, MDJoseph Roberts, PhDEllen Loeb, MDet alAmanullah Khan, MDAyten MacLellan, MDRobert W. Hill, MD

JAMA. 1967;202(9):882-888. doi:10.1001/jama.1967.03130220070012
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