Silicon dioxide or man-made silica is toxic to humans | 二氧化矽或人造二氧化矽對人體健康有毒

Saturday 08/28/2021 (jake.com, healthabc.com) — Silicon dioxide in form of nanoparticles is toxic and it can potentially harm the liver, the kidney, the lung, and the testis, according to a recent animal study.

Environ Sci Pollut Res Int. 2015 Jan;22(2):1127-32. doi: 10.1007/s11356-014-3413-7. Epub 2014 Aug 13.

Titanium dioxide, a nanoparticle commonly used in the past in foods, dietary supplements and medicines has been gradually phased out due to its known toxicity.

Titanium dioxide is toxic largely because it is a nanoparticle which can enter cells freely and the rigidity of the particle can harm many cellular components including DNA, potentially causing mutations.

Silicon dioxide as a nanoparticle is similar to titanium dioxide so it makes sense that it has the same toxicity as titanium dioxide.

The current in vivo study conducted by Ramin Hassankhani from Islamic Azad University in Urmia, Iran finds silicon dioxide nano-particles with “diameters of 10-15 nm in size can cause significant changes in albumin, cholesterol, triglyceride, total protein, urea, HDL, and LDL as well as in alkaline phosphatase and aspartate aminotransferase activity.”

Silicon dioxide nano-particles of this size, which is very commonly used in foods, dietary supplements, and medicines, also cause damages to the liver, the kidney, the lung, and the male reproductive organ testis. (Dr. Lu)

 

二氧化鈦是一種過去常用於食品、膳食補充劑和藥物的納米顆粒,由於其已知的毒性,已逐漸被淘汰。

二氧化鈦之所以有毒,主要是因為它是一種可以自由進入細胞的納米顆粒,而且顆粒的剛性會損害包括 DNA 在內的許多細胞成分,從而可能導致突變。

二氧化矽作為納米顆粒與二氧化鈦相似,因此它具有與二氧化鈦相同的毒性是有道理的。

伊朗烏爾米亞伊斯蘭阿扎德大學的拉明·哈桑卡尼 (Ramin Hassankhani) 目前進行的體內研究發現,“直徑為 10-15 納米的二氧化矽納米顆粒可引起白蛋白、膽固醇、甘油三酯、總蛋白、尿素、高密度脂蛋白的顯著變化和 LDL 以及鹼性磷酸酶和天冬氨酸氨基轉移酶活性。”

這種尺寸的二氧化矽納米顆粒在食品、膳食補充劑和藥物中非常常用,但也會對肝臟、腎臟、肺和男性生殖器官睾丸造成損害。 (陸博士)

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